Product Pipeline

Clinical Applications

Research projects aiming to build a new leading franchise in Immunology and Neurology therapeutics

Clinical Applications

Research projects aiming to build a new leading franchise in Hematology and Thrombosis therapeutics

Clinical Applications

Research projects aiming to build a new leading franchise in Respiratory therapeutics

Clinical Applications

Research projects aiming to build a new leading franchise in Cardiovascular and Metabolic therapeutics

Clinical Applications

Research projects aiming to build a new leading franchise in Transplant therapeutics

CSL964 AAT GvHD

Prevention of acute Graft versus Host Disease (GVHD) in high-risk adolescent and adult patients receiving an allogeneic hematopoietic cell transplant (HCT). Treatment of steroid refractory acute GVHD in adolescent and adult patients

CSL842 C1-INH AMR

C1-esterase inhibitor (C1-INH) for the treatment of refractory antibody mediated rejection (rAMR) in adult renal transplant recipients.

HIZENTRA® IIM

HIZENTRA™, 20% subcutaneous immunoglobulin, for the treatment and long-term maintenance therapy of adults with Idiopathic Inflammatory Myopathies (IIM).

HIZENTRA® CIDP US, Japan, EU, AUS

The first 20% high concentration low volume subcutaneous immunoglobulin for convenient self administration. Approval for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).

PRIVIGEN® PID Japan

PRIVIGEN®, 10% intravenous immunoglobulin, for the treatment of primary immune deficiency (PID) indications in Japan.

PRIVIGEN® CIDP US, Japan

PRIVIGEN®, 10% intravenous immunoglobulin, approved for the treatment of adults with chronic inflammatory demyelinating polyneuropathy (CIDP) to improve neuromuscular disability.

CSL830 C1-INH Subcut, EU

Self-administered subcutaneous C1-esterase inhibitor (human), for routine prophylaxis to prevent HAE attacks in adolescent and adult patients.

HAEGARDA® US

Self-administered subcutaneous C1-esterase inhibitor (human), for routine prophylaxis to prevent HAE attacks in adolescent and adult patients.

KCENTRA® Japan

Lyophilized formulation of plasma-derived concentrate of coagulation factors II, VII, IX, X, Protein C and Protein S used as intravenous administration in patients with acquired deficiency of coagulation factors due to vitamin K antagonist (e.g. Warfarin) therapy.

CSL787 Nebulised Ig

Research program on Nebulised Ig for the potential prevention of chronic respiratory tract infections and progression of chronic lung disease

CSL889 Hemopexin in SCD

Research program on plasma-derived Hemopexin for the potential treatment of Sickle Cell Disease.

CSL200 γ-Globin Gene Therapy in SCD

γ-Globin Gene Therapy for Severe Sickle Cell Disease (SCD).

CSL311 Anti-Beta Common

Fully human monoclonal antibody inhibiting GM-CSF, IL-3 and IL-5 signalling by neutralising the ß-common receptor for the potential treatment of complex inflammatory diseases.

Discovery Projects

Discovery projects aiming to build a new leading franchise in Immunology and Neurology therapeutics

Discovery Projects

Discovery projects aiming to build a new leading franchise in Haematology and Thrombosis therapeutics

Discovery Projects

Discovery projects aiming to build a new leading franchise in Respiratory therapeutics

Discovery Projects

Discovery projects aiming to build a new leading franchise in Cardiovascular and Metabolic therapeutics

Discovery Projects

Discovery projects aiming to build a new leading franchise in Transplant therapeutics

CSL730* rFc Multimer

Novel recombinant human Fc multimer for treatment of patients with immune complex-mediated autoimmune diseases. Developed in collaboration with Momenta Pharmaceuticals.
* Partnered Project

CSL312 Anti-FXIIa in HAE

A humanised anti-factor XIIa monoclonal antibody in development for use in multiple indications including as a subcutaneous therapy for HAE with the potential for administration once every two to three weeks.

CSL324 Anti-G-CSFR

Recombinant Monoclonal Antibody against the cytokine granulocyte colony stimulating factor receptor for the potential development of a new class of drugs that targets arthritis and other inflammatory diseases.

CSL346 Anti-VEGF-B

A humanised mAb that antagonises VEGF-B and is administered via subcutaneous injection either as a standalone therapy or in combination with other agents for the potential treatment of diabetic nephropathy, or other conditions associated with aberrant lipid metabolism.

CSL112 Apo-A1

Novel apolipoprotein A-I infusion therapy developed to reduce the high incidence of early recurrent cardiovascular events that occur in the weeks to months following a heart attack.

CSL334 IL-13R* ASLAN

Monoclonal antibody targeting IL-13Rα1 for the treatment of atopic dermatitis. Licensed to ASLAN Pharmaceuticals.
* Partnered Project

Clazakizumab Anti IL-6 Vitaeris*

Humanized recombinant monoclonal antibody that binds to and inhibits Interleukin-6 (IL-6) as a therapeutic option for solid organ transplant rejection. Development in collaboration with Vitaeris Inc.
* Partnered Project

CSL630 pdFVIII Ruide

Plasma-derived Human Factor VIII manufactured in China through the acquisition of Wuhan Zhong Yuan Rui De Biological Products Co. Ltd. (Ruide).

IDELVION®

Novel, long-acting albumin fusion protein linking recombinant coagulation factor IX with recombinant albumin for the treatment of haemophilia B. Delivers high-level protection with up to 14-day dosing in appropriate patients.

AFSTYLA®

Novel long-lasting recombinant factor VIII single-chain therapy for adults and children with haemophilia A.