What is Hemophilia A?
Hemophilia A is the most common type of hemophilia and is caused by deficient or dysfunctional clotting factor VIII. Although hemophilia A is usually inherited, about 30% of cases are caused by a spontaneous mutation in the person’s own genes.
Hemophilia A affects about 1 in 12,000 people and is diagnosed by taking a blood sample and measuring the level of factor activity in the blood. Hemophilia A is diagnosed by testing the level of factor VIII activity in the blood.
Hemophilia A can be mild, moderate, or severe, depending on how much clotting factor is in an affected person's blood. However, about 60% of patients have the severe form of the disorder. People with hemophilia A have prolonged bleeding after an injury, surgery, or tooth extraction. In severe cases, they may bleed once or twice a week and often the bleeding is spontaneous, which means it happens for no obvious reason. Serious complications can result from bleeding into the joints, muscles, brain, or other internal organs. In a mild case of hemophilia A, the disorder may remain unknown until after a surgery or serious injury.
Treatment for hemophilia A is very effective and with appropriate treatment and care, people with hemophilia A can live perfectly healthy lives. The main treatment is called replacement therapy, during which clotting factor VIII is infused into a vein either prophylactically (preventatively) or on-demand to prevent or treat bleeds.
Outdoor Adventurer Living With Hemophilia A
Hemophilia A Patient
New father and hemophilia A patient Tim Grams enjoys the Colorado outdoors. See how Tim isn't letting this hereditary blood disorder keep him from hiking Dinosaur Ridge or biking at Red Rocks Park.
Here is a sampling of our Vita stories on Hemophilia:
To read all of our stories, please visit our Vita homepage.
Don't Let Hemophilia Hold You Back
Pro golfer Perry Parker’s tips for pursuing dreams despite a rare disease.
Going to School with Hemophilia
Five ways to help your child succeed.
Female Carriers of Hemophilia
Women with a family history of hemophilia could see symptoms like abnormal bleeding.
Resources for you
Availability of treatments may vary from country to country. Please be sure to visit your local CSLBehring.com site for further information.
Current Clinical Trials
Please see below for any current clinical trials for this condition.