Alpha-1 Antitrypsin Deficiency
Understanding Alpha-1 Antitrypsin Deficiency
Alpha-1 is the common name for a genetic condition called alpha-1 antitrypsin deficiency. If you have Alpha-1, your body is unable to produce a protein known as alpha-1 antitrypsin, or A1AT for short. This protein plays an important role in protecting your lungs from damage due to excessive inflammation. Without this protein present in your blood, your lungs may weaken over time and place you at a higher risk for developing serious diseases, such as emphysema and chronic obstructive pulmonary disease (COPD). An abnormal amount of A1AT in the liver can also cause liver disease.
Outdoor enthusiast Alice Wilson was diagnosed with Alpha-1 Antitrypsin Deficiency (Alpha-1) when she was 36 years old. Learn how a simple blood test changed her life.
1 in 1,500 - 3,500
incidence of severe Alpha-1 in people of European descent
20 - 40 yrs. old
typical occurance of first signs and symptoms
estimated carriers of abnormal Alpha-1 genes in the United States
Resources for you
Availability of treatments may vary from country to country. Please be sure to visit your local CSLBehring.com site for further information.