Alpha-1 Patient Alice Walker)

Alpha 1 Antitrypsin Deficiency

Understanding Alpha-1 Antitrypsin Deficiency

Alpha-1 is the common name for a genetic condition called alpha-1 antitrypsin deficiency. If you have Alpha-1, your body is unable to produce a protein known as alpha-1 antitrypsin, or A1AT for short. This protein plays an important role in protecting your lungs from damage due to excessive inflammation. Without this protein present in your blood, your lungs may weaken over time and place you at a higher risk for developing serious diseases, such as emphysema and chronic obstructive pulmonary disease (COPD). An abnormal amount of A1AT in the liver can also cause liver disease.

Alpha-1 Patient Alice Walker

Meet Alice

Outdoor enthusiast Alice Wilson was diagnosed with Alpha 1 Antitrypsin Deficiency (AATD) when she was 36 years old. Learn how a simple blood test changed her life.

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  • 1 in 1,500 - 3,500

    incidence of severe Alpha 1 in people of European descent 

  • 20 - 40 yrs. old

    typical occurance of first signs and symptoms

  • 19 million

    estimated carriers of abnormal Alpha 1 genes in the United States

Resources for you Zemaira CareZ (pronounced “cares”) is a comprehensive support program for those diagnosed with Alpha 1 Antitrypsin Deficiency. Visit Website The Alpha-1 Foundation is committed to finding a cure for Alpha 1 Antitrypsin Deficiency and to improving the lives of people affected by Alpha 1 worldwide. Visit Website

Treatments Available

Availability of treatments may vary from country to country. Please be sure to visit your local site for further information.

Human alpha1-proteinase inhibitor View Website pdf
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