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For Patients
Our Promise to Patients
At CSL we are Driven by Our Promise and guided by our Values: Patient Focus, Innovation, Integrity, Collaboration and Superior Performance.
CSL is committed to putting the patient first in all that we do to discover, develop, and deliver biotherapeutics and vaccines that meet their needs.
We know that every patient is someone’s child, parent, grandparent, family member, friend or colleague. We also understand that rare and serious diseases impact more than just the patient. They also impact their loved ones and the communities that support them.
With that in mind, we strive to deliver therapeutics that meet patient needs, as well as build support systems to create empowerment and community through various programs and activities around the world. We also partner with patient advocacy organizations to improve and expand outreach, education and access to medicines and resources.
Our patients are our passion and that drives the way we work. We are committed to full transparency of expectations and outcomes when partnering with them. We listen closely to patients about their experiences and collaborate with them from early research through the delivery of our innovative medicines. We seek to fully understand their challenges to ensure our research is relevant, meaningful and leads to therapies that result in outcomes that are important to them and make a difference in their lives.
CSL’s Senior Vice President, R&D Strategic Operations Deirdre BeVard attended a company sponsored patient event in May 2022 and was moved to share her experience with CSL employees. Read this re-post from an internal CSL publication.
Our people are the heart of our Patient Focus culture and we strive to earn our patients’ trust every day. CSL employees understand that they are personally accountable for ensuring our interactions with patients are responsible, respectful and humble. We recognize patients as the experts in how diseases impact their lives and we actively seek their insights to guide our efforts.
The commitment of our people to Patient Focus as part of our Values-based culture is essential to delivering on our promise to patients and improving public health.
How can we help you?
Immunodeficiency & Autoimmune Diseases
We offer one of the most comprehensive portfolios of high-quality, technically advanced immunoglobulin (Ig) therapies and we are the leading Ig manufacturer in the world. Treatments are available for the following conditions:
Within the United States:
- Primary Immunodeficiency
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- Idiopathic Thrombocytopenic Purpura (ITP)
Outside the United States:
- Primary Immunodeficiency
- Secondary Immunodeficiency (SID)
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- Idiopathic Thrombocytopenic Purpura (ITP)
- Kawasaki Disease (KD)
- Guillain-Barré Syndrome (GBS)
Hereditary Bleeding Disorders
We are a world leader in innovative medicines for the treatment of bleeding disorders. We offer the largest portfolio for the treatment of hereditary bleeding disorders with more than a dozen plasma-derived and recombinant coagulation factor concentrates. Treatments are available for the following conditions:
Within the United States:
- Hemophilia A
- Hemophilia B
- von Willebrand Disease
- Factor XIII Deficiency
- Fibrinogen Deficiency
Outside the United States:
- Hemophilia A
- Hemophilia B
- von Willebrand Disease
- Factor XIII Deficiency
- Fibrinogen Deficiency
- Factor X Deficiency
Hereditary Angioedema (HAE)
We introduced the world's first subcutaneous preventative treatment for attacks of Hereditary Angioedema (HAE), while still offering our intravenous C1-esterase inhibitor therapy for on-demand treatment.
Alpha 1 Antitrypsin Deficiency
Our Alpha 1 Antitrypsin treats Alpha 1 Antitrypsin Deficiency (AATD) in patients with AATD-related emphysema.
" Get involved. There are tips and tricks other parents learn over the years in raising children with rare disease. Getting that first-hand advice is helpful. "- Madonna McGuire-Smith, mother of children with hemophilia
Find a Clinical Trial
A clinical trial is a research study that is done to find out if medical treatments can improve people’s health. A medical treatment can be a drug, medical device, medical procedure, or a change in a person’s behavior such as diet or exercise. People who take part in clinical trials are volunteers. They are also called “participants."
| Therapeutic Area | Condition | Study Number |
Description | Status (click on link to learn more) |
|---|---|---|---|---|
| Haematology & Thrombosis |
Hemophilia A | OPERA | Register of Patients With haEmophilia A tReated With Afstyla® (OPERA) | Active, Not Recruiting |
| Hemophilia B | OrPHEe | Observatory of Patients With Haemophilia B Treated by IdElvion® | Recruiting | |
| Hemophilia B | CSL220_1002 | Study of AAV5-hFIX in Severe or Moderately Severe Haemophilia B | Active, Not Recruiting | |
| Hemophilia B | CSL222_3001 | HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients |
Active, Not Recruiting | |
| Sickle Cell | CSL889_1001 | A 2-Part, Phase 1, Multi-Center, Single-Dose, Open Label, Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CSL889 in Adult Patients with Sickle Cell Disease |
Recruiting |
|
| Von Willebrand Disease |
OPALE | Registry of Patients With Von WilLEbrand Disease Treated With Voncento® (OPALE) |
Active, Not Recruiting |
|
| Cardiovascular and Metabolic | Acute Coronary Syndrome | CSL112_3001 | Study to investigateCSL112 in Subjects With Acute Coronary Syndrome (AEGIS-II) | Recruiting |
| End Stage Kidney Disease | CSL300_2301 | Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis | Not Yet Recruiting | |
| Diabetic Kidney Disease | CSL346_2001 | A Phase 2a Proof of Concept Study of Vascular Endothelial Growth Factor (VEGF)-B Blockade With the Monoclonal AntibodyCSL346in Subjects With Diabetic Kidney Disease | Recruiting | |
| Immunology and Neurology | Dermatomyositis (DM) | IgPro20_3007 | A study to evaluate the efficacy, safety, and pharmacokinetics of IgPro20 in adults with Dermatomyositis (DM) [RECLAIIM] | Recruiting |
| Pediatric CIDP | IgPro10_4002 | Randomized Study of Single vs. Multiple Privigen Dose Regimens in Pediatric CIDP | Recruiting | |
| Hereditary Angioedema (HAE) |
CSL312_3002 | Long-term Safety and Efficacy of CSL312 (Garadacimab) in the Prophylactic Treatment of Hereditary Angioedema Attacks | Active, Not Recruiting | |
| Hidradenitis Suppurativa and Palmoplantar Pustulosis | CSL324_1002 | A study of the safety and pharmacokinetics of repeat doses ofCSL324in subjects with hidradenitis suppurativa and palmoplantar pustulosis | Active, Not Recruiting | |
| Inflammatory Neuropathy | pHeNIx |
Hizentra® in Inflammatory Neuropathies - pHeNIx Study | Recruiting | |
| Healthy Subjects | CSL312_1004 | A Phase 1 Study to Compare the Pharmacokinetic Properties of CSL312 Administered by Subcutaneous Prefilled Syringe Assembled to Autoinjector to Prefilled Syringe Assembled to Needle Safety Device in Healthy Adult Subjects |
Recruiting | |
| Healthy Subjects | CSL730_1002 | A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SubcutaneousCSL730in Healthy Adult Subjects | Recruiting | |
| Respiratory | Mild Asthma | CSL311_1001 | A Clinical Study to test the safety, exposure, and markers of Efficacy of CSL311 in patients with mild asthma. | Recruiting |
| Idiopathic Pulmonary Fibrosis | CSL312_2002 | CSL312 Safety, Pharmacokinetics, and Pharmacodynamics in Idiopathic Pulmonary Fibrosis | Recruiting | |
| Non-cystic Fibrosis Bronchiectasis (NCFB) |
CSL787_1001 | Study to Assess CSL787 in Non-cystic Fibrosis Bronchiectasis (NCFB) | Recruiting | |
| alpha-1 antitrypsin deficiency |
AmAREtTI Study |
Respreeza® Self-administration and Learning Program (AmAREtTI Study- Auto-Administration de Respreeza® et Programme d'apprenTIssage) |
Recruiting |
|
| Transplant | Antibody-mediated kidney transplant rejection | CSL300_3001 | A Pivotal Phase 3 Trial to Evaluate the Safety and Efficacy of Clazakizumab for the Treatment of Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients [IMAGINE] | Recruiting |
| Acute GVHD (aGVHD) | CSL964_2001 | The Safety and Efficacy of Alpha 1 Antitrypsin (AAT) for the Prevention of Graft‑Versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant [MODULATE] | Recruiting | |
| Graft Versus Host Disease (GVHD) | CSL964_5001 | A study on theefficacy of AAT with corticosteroids compared with corticosteroids alone as first line therapy for patients with high-risk acute GVHD | Recruiting | |
| Chronic Active Antibody Mediated Rejection | AMR BoD | Assess Burden of Disease Among Kidney Transplant Recipients With Chronic Active Antibody Mediated Rejection |
Recruiting | |
|
COMPLETED STUDIES: |
||||
| COVID-19 | COVID-19 | CSL312_COVID-19 | A Phase 2, Multicenter, Double Blind, Randomized, Placebo-Controlled Study to Evaluate CSL312 in Coronavirus Disease 2019 (COVID 19) | Results |
| COVID-19 | CSL324_COVID-19 | CSL324 in COVID‑19 | Withdrawn | |
| COVID-19 | CSL760_1001 | Pharmacokinetics, Safety, and Tolerability of CSL760, an Intravenous Anti-SARS-CoV-2 Hyperimmune Globulin, in Healthy Adult Subjects | Cancelled | |
| Haematology & Thrombosis |
Reversal of acquired coagulation factor deficiency | BE1116_4001 |
An Observational Study to Investigate the Risk of Thromboembolic Events in Patients Receiving Kcentra®or Plasma to Reverse Vitamin K Antagonist (VKA) Therapy in the Setting of Acute Major Bleeding |
Completed |
| Congenital Fibrinogen Deficiency | BI3023_4003 | An Observational Study of the Safety and Efficacy of Fibrinogen Concentrate Human (FCH) in Subjects With Congenital Fibrinogen Deficiency | Completed | |
| Hemophilia A |
CSL627_3001 | An Open-label Safety and Efficacy Study of Recombinant FVIII in Patients With Severe Hemophilia A |
Results | |
| Hemophilia B | CSL222_2001 | Dose Confirmation Trial of AAV5-hFIXco-Padua |
Results |
|
| Hemophilia B | CSL654_3001 | A Safety and Efficacy Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia B |
Results | |
| Hemophilia B | CSL654_3002 | A Safety, Efficacy and Pharmacokinetics Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Children With Hemophilia B |
Results | |
| Hemophilia B | CSL654_3003 | A Safety and Efficacy Extension Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia B |
Results |
|
| Hemophilia B | CT-AMT-060-01 | Trial of AAV5-hFIX in Severe or Moderately Severe Hemophilia B |
Results | |
| Hemophilia A or B | CSL689_2001 | Study of Recombinant Factor VIIa Fusion Protein (rVIIa-FP, CSL689) for On-demand Treatment of Bleeding Episodes in Patients With Hemophilia A or B With Inhibitors | Cancelled | |
| PICC-associated Thrombosis |
CSL312_1002 |
A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line | Withdrawn |
|
| Sickle Cell | CSL200_1001 | CSL200 Gene Therapy in Adults With Severe Sickle Cell Disease |
Cancelled |
|
| Von Willebrand Disease | CSLCT-BIO-12-83 | Study of Voncento®in Subjects With Von Willebrand Disease | Completed | |
| Cardiovascular and Metabolic | Coronary Heart Disease | CSL112_1001 | Assessing the pharmacokinetics, safety, and tolerability of CSL112 in healthy Japanese and Caucasian adults | Completed |
| Renal Impairment and Acute Myocardial Infarction | CSL112_2001 | A Phase 2 Study to Investigate the Safety and Tolerability of Multiple Dose Administration of CSL112 in Subjects With Moderate Renal Impairment and Acute Myocardial Infarction | Results | |
| Acute Myocardial Infarction | CSLCT-HDL-12-77 |
A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction. |
Results |
|
| Immunology and Neurology |
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) | IgPro20_3004 |
Extension Study of Maintenance Treatment with Subcutaneous Immunoglobulin (IgPro20) for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) |
Results |
| Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) |
IgPro10_5004 |
Evaluating the Effectiveness of Telemonitoring System in the Management of Patients With CIDP (HELIPAD 1) |
Cancelled |
|
| Hereditary Angioedema (HAE) | CSL312_2001 |
A study to Investigate CSL312 in Subjects With Hereditary Angioedema (HAE) |
Completed |
|
| Hereditary Angioedema (HAE) |
CSL312_3001 | CSL312 (Garadacimab) in the Prevention of Hereditary Angioedema Attacks |
Completed | |
| Hereditary Angioedema (HAE) |
CSL830_2001 | A Study to Evaluate the Clinical Pharmacology and Safety of C1-esterase Inhibitor Administered by the Subcutaneous Route |
Results | |
| Hereditary Angioedema (HAE) |
CSL830_3001 | A Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema |
Results | |
| Hereditary Angioedema (HAE) | CSL830_3002 | A Study to Evaluate the Long-term Clinical Safety and Efficacy of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema | Results | |
| Hereditary Angioedema (HAE) |
CSL830_3003 |
A Phase 3 study to evaluate clinical efficacy, safety, and pharmacokineti00cs of subcutaneous administration of human plasma derived C1-esterase inhibitor in the prophylactic treatment of hereditary angioedema in Japanese subjects |
Results |
|
| HIV-1 | CAL-USA-11 | An Adaptive Phase I/II Study of the Safety of CAL-USA-11 in HIV-1 Infected Adults Previously Exposed to ART | Results | |
| Primary Immune Deficiency (PID) | IgPro20_1001 | Comparison of 2 Infusion Devices With Respect to Pharmacokinetics, Safety, and Tolerability of Hizentra: An Investigational Wearable Infusor and the Crono S-PID-50 Infusion Pump | Results | |
| Primary Immune Deficiency (PID) | IgPro20_4004 | Safety and Tolerability of Higher Infusion Parameters of IgPro20 (Hizentra®) in Subjects With Primary Immunodeficiency (PID) | Results | |
| Primary Immune Deficiency(PID) | IgPro20_4005 | Study of Immune Deficiency Patients treated with Subcutaneous Immunoglobulin (Hizentra®) on Weekly and Biweekly Schedules | Results | |
| Systemic Sclerosis | IgPro10_2001 | Efficacy and safety study of IgPro10 in adults with Systemic Sclerosis | Withdrawn | |
| Systemic Sclerosis | IgPro20_2001 | A study to investigate the safety, tolerability, and pharmacokinetics ofIgPro20in subjects with diffuse cutaneous systemic sclerosis (dcSSc) |
Completed |
|
| Healthy Subjects | CSL312_1003 | A Study to Assess the Pharmacokinetics and Safety of CSL312 in Healthy Japanese and Caucasian Adults | Completed |
|
| Healthy Subjects | CSL324_1001 | Dose escalation, placebo-controlled phase 1 study to assess the safety and tolerability of CSL324 in healthy adults | Completed | |
| Healthy Subjects | CSL324_1003 | Pharmacokinetics and Safety of Subcutaneous CSL324 in Healthy Japanese and White Subjects |
Completed | |
| Healthy Subjects | CSL730_1001 | Assessing the Safety and Tolerability of CSL730 in Healthy Caucasian and Japanese Adults |
Cancelled |
|
| Transplant | Antibody-mediated kidney transplant rejection | CSL842_3001 | Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR)in Adult Renal Transplant Recipients | Cancelled |
Participate in a Clinical Trial
Discover what is involved in participating in one of our clinical trials and how you can enroll.
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