von Willebrand Disease

What is von Willebrand Disease?

The most common bleeding disorder is von Willebrand disease (VWD) which affects 1% of the world’s population. VWD is typically an inherited disease and caused by deficient or defective von Willebrand Factor (VWF). It occurs in both men and women and is diagnosed by measuring the level and activity of VWF and factor VIII.

There are three main types of von Willebrand disease. Type I is most common and the mildest, and type 3 the rarest and most severe form. Type 3 is usually inherited in an autosomal recessive manner in which the child receives defective gene from both parents. People with type 3 condition have very little or no VWF and experience spontaneous bleeding episodes often into joints and muscles. People with VWD experience prolonged bleeding after injury, surgery, dental work or childbirth. Women with VWD have heavy or prolonged menstrual bleeding.

The treatment depends on the type and severity of VWD. Type 3 patients and patients at risk of severe bleeding in type I and type 2 are often treated with factor concentrates that contain FVIII and are rich in VWF.

Von Willebrand disease patient Kim Walsh

Living Your Life with von Willebrand Disease

Kim Walsh has VWD. Her number one tip: Don't let it limit your life.

Watch Kim's tips

Here is a sampling of our Vita stories on VWD:

To read all of our stories, please visit our Vita homepage.

Woman doctor talking with patient
Rare Disease or Rarely Diagnosed?

New clinical guidelines aim to improve von Willebrand Disease patient outcomes.

Mary Ann VWD patient
Access to Diagnosis, Education and Care

Why a von Willebrand Disease patient is opening a school for kids with cancer.

Milybet and Oscar, hemophilia
Women and Bleeding Disorders – what you need to know

Hemophilia is a disorder that not only affects young males

Resources for you

Signs of Bleeding The 5 signs of a bleeding disorder View Website
World Federation of Hemophilia A global organization aiming to improve and sustain care for people with inherited bleeding disorders.
View Website
National Hemophilia Foundation A U.S. organization dedicated to finding better treatments and cures for inheritable bleeding disorders.
View Website
Hemophilia Federation of America A U.S. a national nonprofit organization that assists and advocates the bleeding disorders community.
View Website

Treatments available

Availability of treatments may vary from country to country. Please be sure to visit your local CSLBehring.com site for further information.

Humate-P® / Haemate® P  Antihemophilic Factor/von Willebrand Factor Complex (Human) Visit Website pdf
Stimate®  (Desmopressin acetate) Nasal Spray, 1.5 mg/mL pdf

Current Clinical Trials

Please see below for any current clinical trials for this condition.

Condition Description    
 von Willebrand Disease Study of Voncento® in Subjects With Von Willebrand Disease Learn More
Group meeting

Participate in Clinical Trials

Discover what is involved in participating in one of our clinical trials and how you can enroll.

Learn More

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