von Willebrand Disease

What is von Willebrand Disease?

The most common bleeding disorder is von Willebrand disease (VWD) which affects 1% of the world’s population. VWD is typically an inherited disease and caused by deficient or defective von Willebrand Factor (VWF). It occurs in both men and women and is diagnosed by measuring the level and activity of VWF and factor VIII.

There are three main types of von Willebrand disease. Type I is most common and the mildest, and type 3 the rarest and most severe form. Type 3 is usually inherited in an autosomal recessive manner in which the child receives defective gene from both parents. People with type 3 condition have very little or no VWF and experience spontaneous bleeding episodes often into joints and muscles. People with VWD experience prolonged bleeding after injury, surgery, dental work or childbirth. Women with VWD have heavy or prolonged menstrual bleeding.

The treatment depends on the type and severity of VWD. Type 3 patients and patients at risk of severe bleeding in type I and type 2 are often treated with factor concentrates that contain FVIII and are rich in VWF.

Resources for you

All About Bleeding Information and resources to help treat and manage life with a bleeding disorder. View Website
All About Bleeding discussion guides View Website
Signs of Bleeding The 5 signs of a bleeding disorder View Website
World Federation of Hemophilia A global organization aiming to improve and sustain care for people with inherited bleeding disorders.
View Website
National Hemophilia Foundation A U.S. organization dedicated to finding better treatments and cures for inheritable bleeding disorders.
View Website
Hemophilia Federation of America A U.S. a national nonprofit organization that assists and advocates the bleeding disorders community.
View Website

Treatments available

Availability of treatments may vary from country to country. Please be sure to visit your local CSLBehring.com site for further information.

Humate-P® / Haemate® P  Antihemophilic Factor/von Willebrand Factor Complex (Human) Visit Website pdf
Stimate®  (Desmopressin acetate) Nasal Spray, 1.5 mg/mL pdf

Current Clinical Trials

Please see below for any current clinical trials for this condition.

Condition Description    
 von Willebrand Disease Study of Voncento® in Subjects With Von Willebrand Disease Learn More
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