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What is a Factor X Deficiency?

Congenital Factor X deficiency is an autosomal recessive inherited bleeding disorder caused by genetic defects on chromosome 13, resulting in a deficiency of Factor X. Mildly affected individuals may have no symptoms but, in more severe cases, people may experience hemorrhagic symptoms, such as nose bleeds or bleeding into the joints or muscles. Factor X deficiency can also be acquired as a result of liver disease, vitamin K deficiency or due to anticoagulants such as warfarin.

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