Pulmonary
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Thought Leadership
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Key Issues Dialogue: Alpha-1
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Related Information
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Alpha-1 Answers
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Related Information
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World COPD Day
 John Walsh, CEO, Alpha-1 Foundation, on testing people with COPD for Alpha-1
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Asthma, emphysema, and chronic obstructive pulmonary disease (COPD) are all breathing problems, and they have something else in common: They may be symptoms of
alpha-1 antitrypsin deficiency.
Alpha-1 deficiency, also known as Alpha-1 or AATD, is a genetic form of COPD. CSL Behring provides alpha1 proteinase inhibitor to treat this chronic lung disease. Alpha1 antitrypsin is a protein produced in the liver that helps protect the lungs. Alpha-1 deficiency is a condition in which a person has little or no alpha1 antitrypsin.
Our
alpha1-proteinase inhibitor Zemaira®
is indicated for chronic augmentation and
maintenance therapy in adults with alpha-1 deficiency and clinical evidence of
emphysema.
Alpha-1 is often misdiagnosed as asthma or emphysema because the symptoms are similar: shortness of breath, chronic cough, difficulty breathing, and wheezing.1 It takes an average of 8.3 years for patients to be diagnosed2. During that time, lung damage progresses. Treatment for COPD alone is not sufficient to thwart the gradual decline of lung function that occurs in patients with underlying alpha1 deficiency3. If untreated, Alpha-1 can cause permanent damage to the lungs. Early diagnosis and treatment are crucial to help those with Alpha-1 have the fullest life possible.
References
1. Alpha1 Foundation - What is Alpha1? Alpha1 Fast Facts. Available at: Alphaone.org.
2. Campos MA, Wanner A, Zhang G, Sandhaus RA. Chest. 2005;128(3):1179-1186.
3. Ranes J, Stoller JK. A review of Alpha1 Antitrypsin deficiency. Semin Respir Crit Care Med. 2005;26:154-166.
Product availability varies from country to country, depending on registration status. Please contact your
CSL Behring representative.
| Condition |
Product Name |
Generic Name |
Product Description |
| Emphysema due to alpha-1 antitrypsin deficiency |
Zemaira® |
Human alpha1-proteinase inhibitor |
Alpha1-proteinase inhibitor
(A1-PI) |