Von Willebrand Disease (VWD)
This Global website is not intended to represent or suggest that particular products are approved or authorized in any particular jurisdiction. You should not construe anything on this website as a promotion or solicitation for any product or service, or as suggesting that a product or service be used where it is not approved or authorized by applicable law and regulation in a particular country, territory, or jurisdiction. To learn which products are approved or authorized in particular countries, please consult the appropriate
View Other Disorders
Von Willebrand Disease
Hemophilia A (Factor VIII Deficiency)
Hemophilia B (Congenital Factor IX Deficiency)
Congenital Fibrinogen (Factor I) Deficiency
Congenital Prothrombin (Factor II) Deficiency
Congenital Factor VII Deficiency
Congenital Factor X Deficiency
Congenital Factor XIII Deficiency
News & Resources
Prof. Heimburger Award Global Research Grant
- More Resources
Von Willebrand Disease (VWD) is a bleeding disorder caused by genetic defects in chromosome 12. These defects cause a deficiency in the quality or quantity of a protein known as von Willebrand Factor (VWF). VWF plays an essential role in the first stage of coagulation.
VWD is the most common inherited bleeding disorder. It is usually mild and does not generally cause spontaneous bleeding.
There are three main types of VWD:
Characterized by decreased levels of VWF and sometimes factor VIII, type 1 is the mildest and most common form of VWD, accounting for around 75% of all cases of VWD.
VWF does not function properly in type 2 VWD. Type 2 is further divided into subtypes, as a result of different gene mutations: 2A, 2B, 2M and 2N.
Characterized by an absence of VWF and decreased levels of factor VIII, type 3 is the most severe form of VWD, but it is very rare.
CSL Behring products
used in the treatment of von Willebrand disease include: