Congenital Prothrombin (Factor II) Deficiency

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Congenital prothrombin (factor II) deficiency is a rare, autosomal recessive inherited bleeding disorder that either causes a reduction in the synthesis of prothrombin (hypoprothrombinemia) or the synthesis of dysfunctional prothrombin (dysprothrombinemia). Common symptoms include easy bruising, nose bleeds and soft-tissue hemorrhage. 12

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