Congenital Factor XIII Deficiency

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Congenital factor XIII deficiency is a rare, autosomal recessive inherited bleeding disorder typically caused by genetic defects on chromosome 6 and usually associated with severe bleeding. In the absence of factor XIII, a blood clot will still develop, but it will remain unstable. The unstable clot will eventually break down and cause recurrent bleeding.

Common symptoms of factor XIII deficiency include soft tissue bleeds,intracranial bleeding, menorrhagia and joint bleeding. 15-16  

CSL Behring products used in the treatment of congenital factor XIII deficiency include:

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